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Aerials (Rifts Book 1)

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Spliethoff HM, Tao L, Shaver SM, Aldous KM, Pass KA, Kannan K, Eadon GA. Use of newborn screening program blood spots for exposure assessment: declining levels of perfluorinated compounds in New York State infants. Environmental Science & Technology. 2008; 42(14):5361–5367. [ PubMed] [ Google Scholar] But Live Active Leisure board member councillor Brawn – and fellow residents who provided distressing deputations to the committee – believe the failure to close the floodgates in time was more than a contributory factor. Councillor Brawn explained: “As you would expect LAL [Live Active Leisure] carries the usual fully comprehensive insurance that any other commercial organisation would have. However, following severe flooding of both Bell’s and the Perth Leisure Pool in August 2020, there is an exclusion on surface water flooding. By 4pm my staff and I abandoned the venue. Obviously the team did everything they could, they tried to salvage what they could on those intervening hours and make safe electrics as best we could as well.”

Taylor KW, Novak RF, Anderson HA, Birnbaum LS, Blystone C, DeVito M, Jacobs D, Köhrle J, Lee D-H, Rylander L. Evaluation of the association between persistent organic pollutants (POPs) and diabetes in epidemiological studies: A national toxicology program workshop review. Environmental Health Perspectives. 2013; 121(7):774–783. [ PMC free article] [ PubMed] [ Google Scholar] T1 - Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models Rhainds M, Levallois P, Dewailly É, Ayotte P. Lead, mercury, and organochlorine compound levels in cord blood in Quebec, Canada. Archives of Environmental Health: An International Journal. 1999; 54(1):40–47. [ PubMed] [ Google Scholar]A report by Perth and Kinross Council’s (PKC) chief executive Thomas Glen admitted floodgates at the North Inch were not closed in time during the extreme weather event on the weekend of October 7 and 8.

Wimmerová S, Lancz K, Tihányi J, Šovčíková E, Kočan A, Drobná B, Palkovičová L’, Jurečková D, Fabišiková A, Čonka K. Half-lives of serum PCB congener concentrations in environmentally exposed early adolescents. Chemosphere. 2011; 82(5):687–691. [ PubMed] [ Google Scholar] This week councillor Bob Brawn told colleagues it seemed “quite apparent” not closing floodgates at Perth’s North Inch in time was not – as the chief executive’s report claimed – a contributory factory but “a major factor”. In July 2022, Live Active Leisure opened its state-of-the-art 100-plus station gym Bell’s Sports Centre to the public. Grandjean P, Budtz-Jørgensen E, Barr DB, Needham LL, Weihe P, Heinzow B. Elimination half-lives of poly chlorinated biphenyl congeners in children. Environmental Science & Technology. 2008; 42(18):6991–6996. [ PMC free article] [ PubMed] [ Google Scholar]Live Active Leisure chief executive Paul Cromwell said: “Obviously we have experienced floods at Bell’s. That’s widely known. Our last most significant one was 2020 which as everyone will remember was described as a one in 100-year flood – but here we are again.” Sun P, Blanchard P, Brice K, Hites RA. Atmospheric organochlorine pesticide concentrations near the Great Lakes: temporal and spatial trends. Environmental Science & Technology. 2006; 40(21):6587–6593. [ PubMed] [ Google Scholar] His report reviewing the local impact of the extreme weather events in October 2023 – which went before PKC’s Scrutiny and Performance Committee on Wednesday November 22 – said this failure “may have contributed to the flooding of some properties”. Louis GMB, Sundaram R, Schisterman EF, Sweeney AM, Lynch CD, Gore-Langton RE, Maisog J, Kim S, Chen Z, Barr DB. Persistent environmental pollutants and couple fecundity: the LIFE study. Environmental Health Perspectives. 2013; 121(2):231–236. [ PMC free article] [ PubMed] [ Google Scholar] Muir DC, Howard PH. Are there other persistent organic pollutants? A challenge for environmental chemists. Environmental Science & Technology. 2006; 40(23):7157–7166. [ PubMed] [ Google Scholar]

Venier M, Hites RA. Time trend analysis of atmospheric POPs concentrations in the Great Lakes region since 1990. Environmental Science & Technology. 2010; 44(21):8050–8055. [ PubMed] [ Google Scholar] He added: “It is worth noting that during Storm Babet – when gates were closed – there was no water ingress at Bell’s. Not – as my colleagues say – definitive proof of any failure but, as is often said in planning, a material consideration. That said, it does show flood prevention works when implemented.” Ha M-H, Lee D-H, Jacobs DR., Jr Association between serum concentrations of persistent organic pollutants and self-reported cardiovascular disease prevalence: results from the National Health and Nutrition Examination Survey, 1999–2002. Environmental Health Perspectives. 2007; 115(8):1204–1209. [ PMC free article] [ PubMed] [ Google Scholar] Louis GMB, Germaine M, Hediger ML, Bell EM, Kus CA, Sundaram R, McLain AC, Yeung E, Hills EA, Thoma ME. Methodology for establishing a population-based birth cohort focusing on couple fertility and children’s development, the Upstate KIDS Study. Paediatric and Perinatal Epidemiology. 2014; 28(3):191–202. [ PMC free article] [ PubMed] [ Google Scholar] Numerous studies have shown that POPs elicit adverse health effects in humans, including disruption of endocrine systems as well as reproductive and immunological effects ( Ha et al. 2007; Morales et al. 2013; Tsuji et al. 2013). For example, serum concentrations of PCBs, p,p′-DDE, and HCB were associated with reduced thyroid hormone levels in adult men ( Meeker et al. 2007). High plasma HCB and PCB concentrations were significantly associated with the risk of developing type 2 diabetes ( Wu et al. 2013). An increased risk for obesity was associated with prenatal exposure to PCBs and DDE in children ( Valvi et al. 2012). In comparison with adults, fetuses, newborns, and infants are more sensitive to the effects of environmental chemicals ( Lignell et al. 2013). POPs have been shown to cross the maternal/trans-placental barrier ( Covaci et al. 2002; Jaraczewska et al. 2006). Owing to the administrative and/or legal restrictions in obtaining blood samples for research purposes, little is known regarding the levels of POPs in newborns.Burse V, DeGuzman M, Korver M, Najam A, Williams C, Hannon W, Therrell B. Preliminary investigation of the use of dried-blood spots for the assessment of in utero exposure to environmental pollutants. Biochemical and Molecular Medicine. 1997; 61(2):236–239. [ PubMed] [ Google Scholar] Vizcaino E, Grimalt JO, Lopez-Espinosa M-J, Llop S, Rebagliato M, Ballester F. Maternal origin and other determinants of cord serum organochlorine compound concentrations in infants from the general population. Environmental Science & Technology. 2010; 44(16):6488–6495. [ PubMed] [ Google Scholar] Persistent organic pollutants (POPs) such as poly chlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) are bio-accumulative, toxic and susceptible to long-range atmospheric transport ( Breivik et al. 2006). Since the 1970s, the use of PCBs and several OCPs was severely restricted or banned in the United States ( Muir and Howard 2006). As a consequence, the levels of these chemicals have decreased in environmental and biological matrixes ( Sun et al. 2006; Venier and Hites 2010). However, detectable levels of PCBs and OCPs have been found in the United States’ general population ( Sjödin et al. 2014). Human exposure and adverse health effects of POPs continue to be of concern despite regulatory efforts to ban the production and use of these chemicals more than 3 decades ago in the United States ( Louis et al. 2013; Taylor et al. 2013; Wu et al. 2013). Morales E, Gascon M, Martinez D, Casas M, Ballester F, Rodríguez-Bernal CL, Ibarluzea J, Marina LS, Espada M, Goñi F. Associations between blood persistent organic pollutants and 25-hydroxyvitamin D3 in pregnancy. Environment International. 2013; 57:34–41. [ PubMed] [ Google Scholar]

Sjödin A, Jones R, Caudill S, Wong L, Turner W, Calafat A. Polybrominated diphenyl ethers, polychlorinated biphenyls, and persistent pesticides in serum from the National Health and Nutrition Examination Survey: 2003–2008. Environmental Science & Technology. 2014; 48:753–760. [ PMC free article] [ PubMed] [ Google Scholar]

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Mr Cromwell said: “Unfortunately the volume of water overwhelmed the arrangements that we had in place that particular weekend.” Jaraczewska K, Lulek J, Covaci A, Voorspoels S, Kaluba-Skotarczak A, Drews K, Schepens P. Distribution of polychlorinated biphenyls, organochlorine pesticides and polybrominated diphenyl ethers in human umbilical cord serum, maternal serum and milk from Wielkopolska region, Poland. Science of the total environment. 2006; 372(1):20–31. [ PubMed] [ Google Scholar] Temporal trends of ΣPCBs (upper) and p,p′-DDE (lower) concentrations in archived dried blood spot samples from NYS newborn screening program, 1997 to 2011 DBS collected from NSP is a valuable resource for studying exposure of newborns to environmental chemicals and for studying temporal trends with exposure to environmental chemicals in newborns. In this study, a gas chromatography-high resolution mass spectrometry method with ultrasonic extraction was successfully applied for the analysis of PCBs and OCPs in DBS samples. This study presents the first evidence of temporal trends of these compounds in DBS specimens collected from newborns during the past two decades. A significant reduction in blood concentrations of PCBs and p,p′-DDE was found between 1997 and 2011. The method developed in this study is applied for a population-based birth cohort with a focus on environmental chemical exposure, couple fertility and children’s health ( Louis et al. 2014).

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